Coyote Bus Lines is a bus service station in South Park.
The bus station has a teal-colored office building where tickets are sold. Buses are parked adjacent to the ticket office. There also lies a restroom building next to the office.
- "Quintuplets 2000" - Kenny busks in the station so that he can get money to travel to Romania.
- "Scott Tenorman Must Die" - Cartman boards a bus bound for Fort Collins, and later finds out that he was tricked by Scott Tenorman into selling pubes there.
- "Something Wall-Mart This Way Comes" - The Boys take a bus ride to Bentonville to seek the president of Wall-Mart. Cartman later joins the group, when his true intention was to stop the rest of the boys from destroying Wall-Mart.